camshaft,
Try a lighter powder charge. I know it's difficult. We all want are bullets screaming downrange. But slowing down your bullet will allow it to hold together better. Work down from your current charge in .3 grain increments till you find another accuracy node. Then, give it a try on game. Sometimes slowing things down just by 150fps. is all it takes. Another thing to look at is the rate of twist on your barrel. Fast twist barrels have a dramatic effect on how the bullet reacts upon impact. They open more violently. If your twist is on the fast side then slowing down the bullet will help. If you try this though, remember to shoot the load for the proper dope.
Tikka